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KMID : 0882420090760040506
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Korean Journal of Medicine
2009 Volume.76 No. 4 p.506 ~ p.509
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A case of acinar cell carcinoma of the pancreas
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Kim Kyu-Young
Lee Hwa-Jung
Ji Jun-Ho
Lee Jung-Lim
Lee Won-Sik
Park Jong-Hoon
Sohn Kyung-Rak
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Abstract
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Acinar cell carcinoma of the pancreas is a rare tumor that constitutes 1~2% of all pancreatic cancers. The clinical and radiologic findings are inconclusive when diagnosing this disease. Acinar cell carcinoma progresses rapidly and metastasizes early, resulting in a poor prognosis. A 41-year-old man was admitted for abdominal pain. Abdominal computed tomography (CT) and positron emission tomography (PET)-CT showed a splenic mass involving the pancreatic tail with increased 18F-fluorodeoxyglucose (18F-FDG) uptake. A primary radical distal pancreatectomy and splenectomy were carried out. The pathology revealed acinar cell carcinoma of the pancreas. Three months later, a gastric recurrence was detected and a total gastrectomy was performed. Four months later, multiple hepatic metastases were found and a left hepatectomy was carried out. During treatment with capecitabine, no evidence of tumor progression was observed for 14 months. We report a case of metastatic pancreatic acinar cell carcinoma that did not progress for 14 months with capecitabine treatment.
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KEYWORD
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Pancreas, Carcinoma, Acinar cell, Capecitabine
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